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Yes. HTTP 1.1 and HTTP 2.0 both work, on rotating Residential and Mobile proxies as well as on ISP proxies. You can confirm it yourself with curl. Replace USERNAME and PASSWORD with your own proxy credentials:
The verbose output names the protocol that was negotiated, so you can read it back from the response. HTTP 2.0 is the protocol version used between your tool and the destination site. It is separate from the proxy protocol you connect with, which is HTTP or SOCKS5. See Protocols and ports.